ML291

This product is for research use only, not for human use. We do not sell to patients.

ML291
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$130To Be Confirmed
10mg$220To Be Confirmed
email: [email protected]        [email protected]

Cat #: V47451 CAS #: 1523437-16-2 Purity ≥ 99%

Description: ML291 is a UPR (unfolded protein response)-inducing sulfabenzamide. ML291 disrupts the adaptive capacity of the UPR and causes apoptosis in multiple solid tumor models. ML291 can activate the apoptotic branch of the UPR, PERK/eIF2a/CHOP, and reduce the burden of leukemia cells.

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Molecular Weight (MW)413.832741737366
Molecular FormulaC16H16CLN3O6S
CAS No.1523437-16-2
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture.

Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4164 mL12.0822 mL24.1644 mL48.3287 mL
5mM0.4833 mL2.4164 mL4.8329 mL9.6657 mL
10mM0.2416 mL1.2082 mL2.4164 mL4.8329 mL
20mM0.1208 mL0.6041 mL1.2082 mL2.4164 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
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Concentration(final)
C2
 
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Volume(final)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.