ML251

This product is for research use only, not for human use. We do not sell to patients.

ML251
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$10503-6 Days
250mg$17903-6 Days
500mg$25403-6 Days
1g$35303-6 Days
email: [email protected]        [email protected]

Cat #: V41200 CAS #: 1486482-16-9 Purity ≥ 99%

Description: ML251 is a potent nanomolar T. brucei and T. cruzi phosphofructokinase (PFK) inhibitor, inhibiting T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for parasite research.

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Molecular Weight (MW)426.27
Molecular FormulaC17H13Cl2N3O4S
CAS No.1486482-16-9
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

SynonymsML251ML-251ML 251
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3459 mL11.7297 mL23.4593 mL46.9186 mL
5mM0.4692 mL2.3459 mL4.6919 mL9.3837 mL
10mM0.2346 mL1.1730 mL2.3459 mL4.6919 mL
20mM0.1173 mL0.5865 mL1.1730 mL2.3459 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
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Concentration(final)
C2
 
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Volume(final)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.