ML-193
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
500mg | $2000 | To Be Confirmed |
1g | $3000 | To Be Confirmed |
5g | $8100 | To Be Confirmed |
Cat #: V25659 CAS #: 713121-80-3 Purity ≥ 98%
Description: ML-193 (ML193; CID-1261822; CID1261822) is a novel and potent GPR55 (G protein-coupled receptor 55) antagonist with IC50 of 221 nM.
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Molecular Weight (MW) | 527.59 |
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Molecular Formula | C28H25N5O4S |
CAS No. | 713121-80-3 |
Protocol | In Vitro | ML-193 (0.01-100 μM; pretreated for 15 min) inhibits β-arrestin trafficking induced by L-α-lysophophosphatidylinositol (LPI, 10 μM) and ML186 (1 μM) with IC50s of 0.22 μM and 0.12 μM, respectively |
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These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 1.8954 mL | 9.4771 mL | 18.9541 mL | 37.9082 mL |
5mM | 0.3791 mL | 1.8954 mL | 3.7908 mL | 7.5816 mL |
10mM | 0.1895 mL | 0.9477 mL | 1.8954 mL | 3.7908 mL |
20mM | 0.0948 mL | 0.4739 mL | 0.9477 mL | 1.8954 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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Molecular Weight*
The dilution calculator equation
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Volume(start)
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.