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MK-7622

This product is for research use only, not for human use. We do not sell to patients.

MK-7622
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$950Check With Us
500mg$1550Check With Us
1g$2325Check With Us
email: [email protected]        [email protected]

Cat #: V4325 CAS #: 1227923-29-6 Purity ≥ 98%

Description: MK-7622 is a novel, potent and highly selective positive allosteric modulator of the M1 muscarinic receptor that has entered Phase II studies in patients with Alzheimer's disease.

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Molecular Weight (MW)399.48
Molecular FormulaC25H25N3O2
CAS No.1227923-29-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5033 mL12.5163 mL25.0325 mL50.0651 mL
5mM0.5007 mL2.5033 mL5.0065 mL10.0130 mL
10mM0.2503 mL1.2516 mL2.5033 mL5.0065 mL
20mM0.1252 mL0.6258 mL1.2516 mL2.5033 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.