MK-4074
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1550 | Check With Us |
| 250mg | $2680 | Check With Us |
| 500mg | $4020 | Check With Us |
: Cat #: V4302 CAS #: 1039758-22-9 Purity ≥ 98%
Description: MK-4074 is a novel, potent and liver-specific inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 which are enzymes that produce malonyl-CoA for fatty acid synthesis, with IC50 values of 3 nM.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 565.62 |
|---|---|
| Molecular Formula | C₃₃H₃₁N₃O₆ |
| CAS No. | 1039758-22-9 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | OC(C1=CN=CC(C2=CC=C(OC3(CCN(C(C4=CC(OC)=C5C(N(C6CC6)C=C5C)=C4)=O)CC3)CC7=O)C7=C2)=C1)=O |
| Synonyms | MK-4074; MK 4074; MK4074; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.7680 mL | 8.8399 mL | 17.6797 mL | 35.3594 mL |
| 5mM | 0.3536 mL | 1.7680 mL | 3.5359 mL | 7.0719 mL |
| 10mM | 0.1768 mL | 0.8840 mL | 1.7680 mL | 3.5359 mL |
| 20mM | 0.0884 mL | 0.4420 mL | 0.8840 mL | 1.7680 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.