Mitomycin C (Ametycine)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
25mg	$90	In Stock
50mg	$130	In Stock
100mg	$210	In Stock
250mg	$370	In Stock
500mg	$620	In Stock

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Cat #: V1426 CAS #: 50-07-7 Purity ≥ 99%

Description: Mitomycin C (Mitozytrex; Mutamycin; Ametycine) is an antineoplastic antibiotic drug that acts by inhibiting DNA synthesis, and has been approved to treat different cancers. Mitomycine C is an analog of methylazirinopyrroloindoledione that has been isolated from Streptomyces caespitosus and other Streptomyces type bacteria. By producing interstrand DNA cross-links, oxygen radicals, and alkylation of DNA, bioreduced mitomycin C inhibits the synthesis of new DNA.

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Molecular Weight (MW)	334.37
Molecular Formula	C15H18N4O5
CAS No.	50-07-7
Storage	Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Synonyms	Ametycine; mitomycine C; Mitomycin; 50-07-7; Ametycine; Mutamycin; Mitomycin-C; Mitocin-C; Ametycin; mitomycinX. US trade names: Mitozytrex; Mutamycin. Foreign brand names: Ametycine; MitocinC; Mitolem; MitoMedac; Mutamycine. Abbreviations: MITC; MITO; MITOC; MTC; NCIC04706

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.9907 mL	14.9535 mL	29.9070 mL	59.8140 mL
5mM	0.5981 mL	2.9907 mL	5.9814 mL	11.9628 mL
10mM	0.2991 mL	1.4953 mL	2.9907 mL	5.9814 mL
20mM	0.1495 mL	0.7477 mL	1.4953 mL	2.9907 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.