Mito-LND (Mito-Lonidamine)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
1mg	$120	To Be Confirmed
5mg	$300	To Be Confirmed
10mg	$490	To Be Confirmed
50mg	$1430	To Be Confirmed
100mg	$2110	To Be Confirmed

: [email protected] [email protected]

Cat #: V41190 CAS #: 2361564-49-8 Purity ≥ 99%

Description: Mito-LND (Mito-Lonidamine) is an orally bioactive inhibitor of oxidative phosphorylation (OXPHOS) that targets mitochondria. Mito-LND inhibits mitochondrial bioenergetics, stimulates the formation of reactive oxygen species, and induces autophagic cell death in lung cancer cells.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	801.6207
Molecular Formula	C43H45BRCL2N3OP
CAS No.	2361564-49-8
Storage	Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.2475 mL	6.2374 mL	12.4747 mL	24.9495 mL
5mM	0.2495 mL	1.2475 mL	2.4949 mL	4.9899 mL
10mM	0.1247 mL	0.6237 mL	1.2475 mL	2.4949 mL
20mM	0.0624 mL	0.3119 mL	0.6237 mL	1.2475 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.