Mirodenafil dihydrochloride

This product is for research use only, not for human use. We do not sell to patients.

Mirodenafil dihydrochloride
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10mg$80To Be Confirmed
50mg$220To Be Confirmed
100mg$340To Be Confirmed
email: [email protected]        [email protected]

Cat #: V18977 CAS #: 862189-96-6 Purity ≥ 99%

Description: Mirodenafil (SK3530) diHCl is an orally bioavailable, reversible, selective inhibitor of phosphodiesterase 5 (PDE5). Mirodenafil diHCl is a modulator of the glucocorticoid receptor (GR). Mirodenafil diHCl activates the Wnt/β-catenin signaling pathway by downregulating the expression of Dkk1. Mirodenafil diHCl is used to study erectile dysfunction (ED), Alzheimer's disease (AD) and systemic sclerosis (SSc).

Top Publications Citing Invivochem Products
Product Catalog 2022
Bulletin Board
Guide to Product Handling
Publications Citing InvivoChem Products
Product Promise
Promise
Molecular Weight (MW)604.588
Molecular FormulaC26H39Cl2N5O5S
CAS No.862189-96-6
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture.

SynonymsMirodenafil Dihydrochloride SK3530 M-vix SK-3530SK-3530 dihydrochloride SK 3530
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.6540 mL8.2701 mL16.5402 mL33.0804 mL
5mM0.3308 mL1.6540 mL3.3080 mL6.6161 mL
10mM0.1654 mL0.8270 mL1.6540 mL3.3080 mL
20mM0.0827 mL0.4135 mL0.8270 mL1.6540 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.