Miltefosine (Impavido; HePC)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $160 | Check With Us |
| 5g | $450 | Check With Us |
| 10g | $675 | Check With Us |
: Cat #: V0166 CAS #: 58066-85-6 Purity ≥ 98%
Description: Miltefosine (Impavido; HePC), an alkyl-phosphocholine compound, is a potent, orally- and topically-bioactive, broad spectrum antimicrobial and anti-leishmanial medication that also has potential antineoplastic activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 407.57 |
|---|---|
| Molecular Formula | C21H46NO4P |
| CAS No. | 58066-85-6 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: <1 mg/mLr |
| Water: 82 mg/mL (201.2 mM)r | |
| Ethanol: 82 mg/mL (201.2 mM) | |
| Solubility In Vivo | Saline: 30mg/mL |
| SMILES Code | O=P(OCCCCCCCCCCCCCCCC)([O-])OCC[N+](C)(C)C |
| Synonyms | Miltefosin CHePCHexadecylphosphocholineHDPCHexadecylphosphorylcholineMiltefosinum; Miltefosin; Miltefosina; Miltefosinum; mpavido; Miltex; Choline Phosphate Hexadecyl Ester Hydroxide Inner Salt; hexadecylphosphocholine; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.4536 mL | 12.2678 mL | 24.5357 mL | 49.0713 mL |
| 5mM | 0.4907 mL | 2.4536 mL | 4.9071 mL | 9.8143 mL |
| 10mM | 0.2454 mL | 1.2268 mL | 2.4536 mL | 4.9071 mL |
| 20mM | 0.1227 mL | 0.6134 mL | 1.2268 mL | 2.4536 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.