MG-101 (ALLN)

This product is for research use only, not for human use. We do not sell to patients.

MG-101 (ALLN)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$750Check With Us
500mg$1150Check With Us
1g$1725Check With Us

Cat #: V0705 CAS #: 110044-82-1 Purity ≥ 98%

Description: MG-101 (also known as MG101; Calpain Inhibitor I and ALLN) is a novel, cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins with potential antitumor activity.

References: Li SZ, et al. ALLN hinders HCT116 tumor growth through Bax-dependent apoptosis. Biochem Biophys Res Commun. 2013 Jul 26;437(2):325-330.

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Product Promise

Promise
Molecular Weight (MW)383.53
Molecular FormulaC20H37N3O4
CAS No.110044-82-1
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 76 mg/mL (198.2 mM)r
Water: <1 mg/mLr
Ethanol: 76 mg/mL (198.2 mM)
SMILES CodeCC(C)C[C@H](NC(C)=O)C(N[C@@H](CC(C)C)C(N[C@H](CCCC)C=O)=O)=O
SynonymsMG101; ALLN; AcLLnLCHO; Calpain Inhibitor I; MG-101; MG 101; Ac-Leu-Leu-Nle-Aldehyde.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6074 mL13.0368 mL26.0736 mL52.1472 mL
5mM0.5215 mL2.6074 mL5.2147 mL10.4294 mL
10mM0.2607 mL1.3037 mL2.6074 mL5.2147 mL
20mM0.1304 mL0.6518 mL1.3037 mL2.6074 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.