MF-094

This product is for research use only, not for human use. We do not sell to patients.

MF-094
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Cat #: V31474 CAS #: 2241025-68-1 Purity ≥ 99%

Description: MF-094 (MF094) is a novel and potent USP30 inhibitor (IC50 = 120 nM). USP30 is an enzyme that de-ubiquitinates mitochondrial proteins; therefore, inhibiting this enzyme could foster mitophagy. MF-094 acts by increasing protein ubiquitination and accelerates mitophagy.

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Molecular Weight (MW)535.70
Molecular FormulaC₃₀H₃₇N₃O₄S
CAS No.2241025-68-1
SMILES Code CC(C)(C)NS(C1=CC=CC2=C1C=CC=C2NC([C@H](CC3=CC=CC=C3)NC(C4CCCCC4)=O)=O)(=O)=O
Synonyms MF-094; MF 094
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8667 mL9.3336 mL18.6672 mL37.3343 mL
5mM0.3733 mL1.8667 mL3.7334 mL7.4669 mL
10mM0.1867 mL0.9334 mL1.8667 mL3.7334 mL
20mM0.0933 mL0.4667 mL0.9334 mL1.8667 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.