Meprednisone (Betapar)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$950	Check With Us
500mg	$1450	Check With Us
1g	$2175	Check With Us

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Cat #: V1712 CAS #: 1247-42-3 Purity ≥ 98%

Description: Meprednisone (formerly NSC-527579; SCH-4358; NSC63278; SCH4358; Betapar; Medrysone) is a glucocorticoid and a methylated derivative of prednisone acting as a glucocorticoid receptor agonist and has been approved for use to treat allergic and inflammatory of the eye.

References: Scheuer, E. and E. Warshaw, Allergy to corticosteroids: update and review of epidemiology, clinical characteristics, and structural cross-reactivity. Am J Contact Dermat, 2003. 14(4): p. 179-87.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	372.45
Molecular Formula	C22H28O5
CAS No.	1247-42-3
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 75 mg/mL (201.3 mM)r
	Water: <1 mg/mLr
	Ethanol: 4 mg/mL (10.7 mM)
Synonyms	NSC-63278; Betapar; Medrysone; NSC 63278; NSC63278

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.6849 mL	13.4246 mL	26.8492 mL	53.6985 mL
5mM	0.5370 mL	2.6849 mL	5.3698 mL	10.7397 mL
10mM	0.2685 mL	1.3425 mL	2.6849 mL	5.3698 mL
20mM	0.1342 mL	0.6712 mL	1.3425 mL	2.6849 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.