Melanotan I (Afamelanotide; CUV1647)

This product is for research use only, not for human use. We do not sell to patients.

Melanotan I (Afamelanotide; CUV1647)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$903-6 Days
10mg$1403-6 Days
25mg$2303-6 Days
50mg$3403-6 Days
email: [email protected]        [email protected]

Cat #: V29413 CAS #: 75921-69-6 Purity ≥ 99%

Description: Afamelanotide (Melanotan I; MT-I; CUV-1647; MBJ05; trade name Scenesse) is a synthetic peptide analog of α-melanocyte stimulating hormone (α-MSH), acting as a melanocortin receptor agonist and has been approved for use to prevent skin damage from the sun in people with erythropoietic protoporphyria in EU and USA. Skin becomes darker as a result (it produces more melanin and gets tan).

Top Publications Citing Invivochem Products
Product Catalog 2022
Bulletin Board
Guide to Product Handling
Publications Citing InvivoChem Products
Product Promise
Promise
Molecular Weight (MW)1646.84524
Molecular FormulaC78H111N21O19
CAS No.75921-69-6
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: (1). This product is not stable in solution, please use freshly prepared working solution for optimal results.  (2). Please store this product in a sealed and protected environment, avoid exposure to moisture.

SynonymsCUV-1647; CUV 1647; CUV1647; Afamelanotide; MBJ-05; MBJ 05; MBJ05; Melanotan I; MT-I; [Nle4,D-Phe7]-α-MSH
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM0.6072 mL3.0361 mL6.0722 mL12.1444 mL
5mM0.1214 mL0.6072 mL1.2144 mL2.4289 mL
10mM0.0607 mL0.3036 mL0.6072 mL1.2144 mL
20mM0.0304 mL0.1518 mL0.3036 mL0.6072 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.