Melanotan I (Afamelanotide; CUV1647)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
50mg	$1250	To Be Confirmed
100mg	$1875	To Be Confirmed
200mg	$2815	To Be Confirmed

: [email protected] [email protected]

Cat #: V29413 CAS #: 75921-69-6 Purity ≥ 99%

Description: Afamelanotide (Melanotan I; MT-I; CUV-1647; MBJ05; trade name Scenesse) is a synthetic peptide analog of α-melanocyte stimulating hormone (α-MSH), acting as a melanocortin receptor agonist and has been approved for use to prevent skin damage from the sun in people with erythropoietic protoporphyria in EU and USA.

References: Langan EA, et al. Melanotropic peptides: more than just 'Barbie drugs' and 'sun-tan jabs'? Br J Dermatol. 2010 Sep;163(3):451-5.

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Molecular Weight (MW)	1646.85
Molecular Formula	C78H111N21O19
CAS No.	75921-69-6

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	0.6072 mL	3.0361 mL	6.0722 mL	12.1444 mL
5mM	0.1214 mL	0.6072 mL	1.2144 mL	2.4289 mL
10mM	0.0607 mL	0.3036 mL	0.6072 mL	1.2144 mL
20mM	0.0304 mL	0.1518 mL	0.3036 mL	0.6072 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.