Mebendazole
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
2g | $150 | Check With Us |
5g | $250 | Check With Us |
10g | $375 | Check With Us |
Cat #: V16923 CAS #: 31431-39-7 Purity ≥ 98%
Description: Mebendazole is an Antihelminthic.
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Molecular Weight (MW) | 295.3 |
---|---|
Molecular Formula | C16H13N3O3 |
CAS No. | 31431-39-7 |
Synonyms | Mebendazole; Vermox; Telmin; Pantelmin; Mebenvet; Telmin; Vermicol; Vermidil; Vermin; Vermox; Wormkuur |
Protocol | In Vitro | Mebendazole (0.1 μM and 1 μM; 24 h) Disruption of microtubule aggregation and microtubule structure in 060919 glioblastoma multiforme (GBM) cells |
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In Vivo | Mebendazole (50 mg/kg; p.o.; once daily for first 20 d and 5 d per week with 2 d off; 45) Inhibition of intracranial tumor growth in the homologous GL261 mouse model and 060919 human glioblastoma multiforme (GBM) xenograft mouse model | |
Animal model | C57BL/6 mice (5-6 weeks old) implanted with GL261 glioma cells and 060919 human glioblastoma multiforme (GBM) |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 3.3864 mL | 16.9319 mL | 33.8639 mL | 67.7277 mL |
5mM | 0.6773 mL | 3.3864 mL | 6.7728 mL | 13.5455 mL |
10mM | 0.3386 mL | 1.6932 mL | 3.3864 mL | 6.7728 mL |
20mM | 0.1693 mL | 0.8466 mL | 1.6932 mL | 3.3864 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.