MB-10
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50mg | $750 | In Stock |
| 100mg | $1250 | In Stock |
| 200mg | $1875 | In Stock |
: Cat #: V2243 CAS #: 394694-98-5 Purity ≥ 98%
Description: MB-10, also known as MitoBloCK-10, is a novel, potent and first-in-class small molecule modulator that can attenuate the activity of protein-associated motor (PAM) complex.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 293.27 |
|---|---|
| Molecular Formula | C12H8FN3O3S |
| CAS No. | 394694-98-5 |
| Protocol | In Vitro | MB-10 (100 μM) is a potential attenuator for protein input into mitochondria. The MB-10 suppresses substrate input using the TIM23 input path. MB-10 (0-100 μM) inhibits protein entry into mammalian mitochondria. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.4098 mL | 17.0491 mL | 34.0983 mL | 68.1965 mL |
| 5mM | 0.6820 mL | 3.4098 mL | 6.8197 mL | 13.6393 mL |
| 10mM | 0.3410 mL | 1.7049 mL | 3.4098 mL | 6.8197 mL |
| 20mM | 0.1705 mL | 0.8525 mL | 1.7049 mL | 3.4098 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.