Maxacalcitol-D6

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
5mg	$7250	To Be Confirmed
10mg	$10935	To Be Confirmed
20mg	$16400	To Be Confirmed

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Cat #: V41330 CAS #: Maxacalcitol-D6 Purity ≥ 99%

Description: Maxacalcitol-D6 is the hexa-deuterated form (at the 26,27-dimethyl group) of Maxacalcitol which is a novel calcitriol analog without hypercalcemic side effects. Maxacalcitol (22-Oxacalcitriol) acts as a VDR agonist. Reference: Res.Vet.Sci. (2000)68 79.

References: [1]. Monier-Faugere et al 22-Oxacalcitriol suppresses secondary hyperparathyroidism without inducing low bone turnover in dogs with renal failure. Kidney Int. (1999)55 821.

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Molecular Weight (MW)	424.65
Molecular Formula	C26H36D6O4
CAS No.	Maxacalcitol-D6
Solubility In Vitro	DMSO : 100 mg/mL (235.49 mM; Need ultrasonic)
Synonyms	Maxacalcitol-d6;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.3549 mL	11.7744 mL	23.5488 mL	47.0976 mL
5mM	0.4710 mL	2.3549 mL	4.7098 mL	9.4195 mL
10mM	0.2355 mL	1.1774 mL	2.3549 mL	4.7098 mL
20mM	0.1177 mL	0.5887 mL	1.1774 mL	2.3549 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.