Marimastat (BB-2516)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1050 | Check With Us |
| 500mg | $1600 | Check With Us |
| 1g | $2400 | Check With Us |
: Cat #: V0739 CAS #: 154039-60-8 Purity ≥ 98%
Description: Marimastat (formerly aslo known as BB2516; BB-2516; TA2516; TA-2516) is an orally bioactive and broad spectrum matrix metalloprotease (MMP) inhibitor with potential anticancer activity.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 331.41 |
|---|---|
| Molecular Formula | C15H29N3O5 |
| CAS No. | 154039-60-8 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 54 mg/mL (162.9 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 7 mg/mL (21.1 mM) | |
| Solubility In Vivo | 50% DMSO+PBS: 30 mg/mL |
| SMILES Code | O=C(N[C@@H](C(C)(C)C)C(NC)=O)[C@H](CC(C)C)[C@H](O)C(NO)=O |
| Synonyms | BB 2516; TA-2516; Marimastat; BB-2516; BB2516; TA2516; TA 2516 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.0174 mL | 15.0871 mL | 30.1741 mL | 60.3482 mL |
| 5mM | 0.6035 mL | 3.0174 mL | 6.0348 mL | 12.0696 mL |
| 10mM | 0.3017 mL | 1.5087 mL | 3.0174 mL | 6.0348 mL |
| 20mM | 0.1509 mL | 0.7544 mL | 1.5087 mL | 3.0174 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.