Madecassic acid

This product is for research use only, not for human use. We do not sell to patients.

Madecassic acid
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$400To Be Confirmed
2g$650To Be Confirmed
5g$1100To Be Confirmed

Cat #: V34348 CAS #: 18449-41-7 Purity ≥ 99%

Description: Madecassic acid is natural product of the triterpenoid class isolated from Centella asiatica (Umbelliferae).

References: Won JH, et al. Anti-inflammatory effects of madecassic acid via the suppression of NF-kappaBpathway in LPS-induced RAW 264.7 macrophage cells. Planta Med. 2010 Feb;76(3):251-7.

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Molecular Weight (MW)504.70
Molecular FormulaC30H48O6
CAS No.18449-41-7
SMILES Code O=C([C@]12CC[C@@H](C)[C@H](C)C1C3=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@@]4(C)[C@]3(C)CC2)O
SynonymsMadecassic acid
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9814 mL9.9069 mL19.8138 mL39.6275 mL
5mM0.3963 mL1.9814 mL3.9628 mL7.9255 mL
10mM0.1981 mL0.9907 mL1.9814 mL3.9628 mL
20mM0.0991 mL0.4953 mL0.9907 mL1.9814 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.