m-PEG3-amine
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
1g | $500 | Check With Us |
5g | $950 | Check With Us |
10g | $1425 | Check With Us |
Cat #: V25849 CAS #: 74654-07-2 Purity ≥ 99%
Description: m-PEG3-amine is a PEG analogue containing an amino group.
References: Nianhe Han, et al. The derivant of aplysiatoxin 10 and application thereof. CN106279352A.
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Molecular Weight (MW) | 163.21 |
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Molecular Formula | C7H17NO3 |
CAS No. | 74654-07-2 |
SMILES Code | NCCOCCOCCOC |
Synonyms | m-PEG3-amin |
Protocol | In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 6.1271 mL | 30.6354 mL | 61.2708 mL | 122.5415 mL |
5mM | 1.2254 mL | 6.1271 mL | 12.2542 mL | 24.5083 mL |
10mM | 0.6127 mL | 3.0635 mL | 6.1271 mL | 12.2542 mL |
20mM | 0.3064 mL | 1.5318 mL | 3.0635 mL | 6.1271 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.