LY-2452473
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $659 | To Be Confirmed |
| 500mg | $939 | To Be Confirmed |
| 1g | $1409 | To Be Confirmed |
: Cat #: V4852 CAS #: 1029692-15-6 Purity ≥ 99%
Description: LY2452473 is a novel, potent, selective and orally bioavailable androgen receptor modulator (SARM) with potential tissue-selective androgenic/anti-androgenic activity.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 374.44 |
|---|---|
| Molecular Formula | C22H22N4O2 |
| CAS No. | 1029692-15-6 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| SMILES Code | O=C(OC(C)C)N[C@H](C1)CC2=C1N(CC3=NC=CC=C3)C4=C2C=C(C#N)C=C4 |
| Synonyms | LY2452473; LY-2452473; LY 2452473 |
| Protocol | In Vivo | LY2452473 is a selective androgen receptor modulator being developed for the treatment of disorders related to hypogonadism. LY2452473 is absorbed rapidly (time to reach maximum plasma concentration for both LY2452473 and total radioactivity is 2-3 h) and cleared slowly (plasma terminal t1/2 of 27 h for LY2452473 and 51 h for the total radioactivity). |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.6707 mL | 13.3533 mL | 26.7065 mL | 53.4131 mL |
| 5mM | 0.5341 mL | 2.6707 mL | 5.3413 mL | 10.6826 mL |
| 10mM | 0.2671 mL | 1.3353 mL | 2.6707 mL | 5.3413 mL |
| 20mM | 0.1335 mL | 0.6677 mL | 1.3353 mL | 2.6707 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
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Concentration(final)
C2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.