LP-533401 HCl

This product is for research use only, not for human use. We do not sell to patients.

LP-533401 HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$550Check With Us
250mg$800Check With Us
500mg$1200Check With Us

Cat #: V18911 CAS #: 1040526-12-2 Purity ≥ 98%

Description: LP-533401 HCl is an inhibitor of tryptophan hydroxylase-1 (Tph-1), the initial enzyme in gut-derived serotonin (GDS) biosynthesis..

References: Yadav, V.K., et al. Inhibition of gut-derived serotonin synthesis: A potential bone anabolic treatment. Nat. Med. 16(3), 308-312 (2010).

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Promise
Molecular Weight (MW)562.94
Molecular FormulaC27H23ClF4N4O3
CAS No.1040526-12-2
SMILES CodeO=C(O)[C@@H](N)CC1=CC=C(C2=NC(N)=NC(OC(C3=CC=C(C4=CC=CC(F)=C4)C=C3)C(F)(F)F)=C2)C=C1.[H]Cl
SynonymsLP 533401 Hydrochloride; LP533401 Hydrochloride; LP-533401 HCl; LP 533401 HCl; LP533401 HCl; LP-533401 Hydrochloride;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.7764 mL8.8819 mL17.7639 mL35.5278 mL
5mM0.3553 mL1.7764 mL3.5528 mL7.1056 mL
10mM0.1776 mL0.8882 mL1.7764 mL3.5528 mL
20mM0.0888 mL0.4441 mL0.8882 mL1.7764 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.