Lotrafiban

This product is for research use only, not for human use. We do not sell to patients.

Lotrafiban
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Cat #: V5457 CAS #: 171049-14-2 Purity ≥ 99%

Description: Lotrafiban is a novel and potent nonpeptide antagonist of the human platelet fibrinogen receptor (glycoprotein IIb/IIIa)

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Molecular Weight (MW)428.53
Molecular FormulaC23H32N4O4
CAS No.171049-14-2
SynonymsLotrafiban; SB-214857; SB 214857; SB214857
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3336 mL11.6678 mL23.3356 mL46.6712 mL
5mM0.4667 mL2.3336 mL4.6671 mL9.3342 mL
10mM0.2334 mL1.1668 mL2.3336 mL4.6671 mL
20mM0.1167 mL0.5834 mL1.1668 mL2.3336 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.