Longdaysin

This product is for research use only, not for human use. We do not sell to patients.

Longdaysin
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$900To Be Confirmed
500mg$1550To Be Confirmed
1g$2325To Be Confirmed

Cat #: V5237 CAS #: 1353867-91-0 Purity ≥ 99%

Description: Longdaysin is a novel and potent inhibitor of Casein Kinase (CK1α, CK1δ, CDK7) and ERK2 with IC50s of  5.6 µM, 8.8 µM, 29 µM, and 52 µM, respectively.

References: Griffett K, et al. The mammalian clock and chronopharmacology. Bioorganic & Medicinal Chemistry Letters, 2013, 23(7):1929-1934..

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)335.33
Molecular FormulaC16H16F3N5
CAS No.1353867-91-0
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9821 mL14.9107 mL29.8214 mL59.6427 mL
5mM0.5964 mL2.9821 mL5.9643 mL11.9285 mL
10mM0.2982 mL1.4911 mL2.9821 mL5.9643 mL
20mM0.1491 mL0.7455 mL1.4911 mL2.9821 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.