Liquiritoside

This product is for research use only, not for human use. We do not sell to patients.

Liquiritoside
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$350Check With Us
250mg$550Check With Us
500mg$825Check With Us

Cat #: V12766 CAS #: 551-15-5 Purity ≥ 99%

Description: Liquiritoside is a naturally occurring flavonoid isolated from Glycyrrhiza with antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity.

References: Zeng C, et al. Liquiritin, as a Natural Inhibitor of AKR1C1, Could Interfere With the Progesterone Metabolism. Front Physiol. 2019 Jul 3;10:833.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)418.39
Molecular FormulaC21H22O9
CAS No.551-15-5
SMILES Code O=C1C[C@@H](C2=CC=C(O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C=C2)OC4=CC(O)=CC=C14
SynonymsLiquiritoside; Likviritin; Liquiritin;
ProtocolIn VitroLiquiritin (50 μM; 6 hours) results in 85.00% of reduction in progesterone metabolism, which is mediated by Aldo-keto reductase family 1 member C1 (AKR1C1) enzymatic activity in HEC-1-B cells. Liquiritin can target the residues Ala-27, Val-29, Ala-25, and Asn-56 of AKR1C1.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3901 mL11.9506 mL23.9011 mL47.8023 mL
5mM0.4780 mL2.3901 mL4.7802 mL9.5605 mL
10mM0.2390 mL1.1951 mL2.3901 mL4.7802 mL
20mM0.1195 mL0.5975 mL1.1951 mL2.3901 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.