Liproxstatin-1

This product is for research use only, not for human use. We do not sell to patients.

Liproxstatin-1
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$950In Stock
500mg$1250In Stock
1g$1875In Stock

Cat #: V0956 CAS #: 950455-15-9 Purity ≥ 98%

Description: Liproxstatin-1 (Lip-1) is a novel and potent inhibitor of ferroptosis with important biological activity.

References: Friedmann Angeli JP, et al. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat Cell Biol. 2014 Dec;16(12):1180-91.

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Product Promise

Promise
Molecular Weight (MW)340.85
Molecular FormulaC19H21ClN4
CAS No.950455-15-9
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 68 mg/mL (199.5 mM)r
Water: <1 mg/mLr
Ethanol: 21 mg/mL (61.6 mM)
SMILES CodeClC1=CC(CNC(C23CCNCC2)=NC4=C(N3)C=CC=C4)=CC=C1
SynonymsLiproxstatin-1; Chemical Name: N-[(3-Chlorophenyl)methyl]-spiro[piperidine-4,2′(1′H)-quinoxalin]-3′-amine
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9338 mL14.6692 mL29.3384 mL58.6768 mL
5mM0.5868 mL2.9338 mL5.8677 mL11.7354 mL
10mM0.2934 mL1.4669 mL2.9338 mL5.8677 mL
20mM0.1467 mL0.7335 mL1.4669 mL2.9338 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.