Lipoic Acid [R-(+)-Thioctic acid]
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
10g | $250 | Check With Us |
25g | $350 | Check With Us |
50g | $525 | Check With Us |
Cat #: V12281 CAS #: 1200-22-2 Purity ≥ 98%
Description: Lipoic Acid, formerly known as R-(+)-alpha-Lipoic acid, is an organosulfur compound derived from octanoic acid.
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Molecular Weight (MW) | 206.33 |
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Molecular Formula | C8H14O2S2 |
CAS No. | 1200-22-2 |
Protocol | In Vitro | Lipoic acid ((R)-(+)-α-Lipoic acid) is a form of human biosynthesis that is essential for aerobic metabolism. Lipoic acid ((R)-(+)-α-Lipoic acid) is the preferred form in nutrition and processing because of its "vitamin-like" effects in metabolism. Lipoic acid ((R)-(+)-α-Lipoic acid) and S-(-)-α- Lipoic acid) constitute the racemic mixture Lipoic acid. Only Lipoic acid (((R)-(+)-α-Lipoic acid) exists in nature and is an essential cofactor for the four mitochondrial enzyme complexes. Lipoic acid ((R)-(+)-α-Lipoic acid) is considered the preferred form of antioxidant for nutrition and processing |
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These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 4.8466 mL | 24.2330 mL | 48.4660 mL | 96.9321 mL |
5mM | 0.9693 mL | 4.8466 mL | 9.6932 mL | 19.3864 mL |
10mM | 0.4847 mL | 2.4233 mL | 4.8466 mL | 9.6932 mL |
20mM | 0.2423 mL | 1.2117 mL | 2.4233 mL | 4.8466 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.