Liothyronine sodium

This product is for research use only, not for human use. We do not sell to patients.

Liothyronine sodium
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$650Check With Us
10g$990Check With Us
20g$1485Check With Us

Cat #: V30180 CAS #: 55-06-1 Purity ≥ 99%

Description: Liothyronine sodium, the sodium of liothyronine, is a potent agonist of both thyroid hormone receptors TRα and TRβ.

References: Lin KH, et al. Stimulation of proliferation by 3,3',5-triiodo-L-thyronine in poorly differentiated human hepatocarcinoma cells overexpressing beta 1 thyroid hormone receptor. Cancer Lett. 1994 Oct 14;85(2):189-94.

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Molecular Weight (MW)672.96
Molecular FormulaC15H11I3NNaO4
CAS No.55-06-1
SMILES CodeO=C([O-])[C@@H](N)CC1=CC(I)=C(OC2=CC=C(O)C(I)=C2)C(I)=C1.[Na+]
SynonymsLiothyronine; Triiodothyronine; 3,3',5-Triiodo-L-thyronine; Liothyronin; Tresitope; 3,5,3'-triiodothyronine; Cytomel; Tertroxin
ProtocolIn VitroLiothyronine (T3, 100 nM) sodium stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.4860 mL7.4299 mL14.8597 mL29.7194 mL
5mM0.2972 mL1.4860 mL2.9719 mL5.9439 mL
10mM0.1486 mL0.7430 mL1.4860 mL2.9719 mL
20mM0.0743 mL0.3715 mL0.7430 mL1.4860 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
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Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.