Lidocaine (Lignocaine)

This product is for research use only, not for human use. We do not sell to patients.

Lidocaine (Lignocaine)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25g$200Check With Us
50g$350Check With Us
100g$525Check With Us

Cat #: V1215 CAS #: 137-58-6 Purity ≥ 98%

Description: Lidocaine (Alphacaine; NSC-40030; NSC40030; Lignocaine), a local anesthetic and cardiac depressant used as an antiarrhythmia agent, is a potent and selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.

References: Sui H, et al. Lidocaine inhibits growth, migration and invasion of gastric carcinoma cells by up-regulation of miR-145. BMC Cancer. 2019 Mar 15;19(1):233.

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Molecular Weight (MW)234.34
Molecular FormulaC14H22N2O
CAS No.137-58-6
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 47 mg/mL (200.6 mM)rr
Water: 9 mg/mL (38.4 mM)rr
Ethanol: 47 mg/mL (200.6 mM)
SynonymsNSC 40030; Alphacaine; NSC-40030; NSC40030
ProtocolIn VitroLidocaine (Lignocaine) (10 nM; 48 hours) decreases significantly cell proliferation
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.2673 mL21.3365 mL42.6730 mL85.3461 mL
5mM0.8535 mL4.2673 mL8.5346 mL17.0692 mL
10mM0.4267 mL2.1337 mL4.2673 mL8.5346 mL
20mM0.2134 mL1.0668 mL2.1337 mL4.2673 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.