Licochalcone C

This product is for research use only, not for human use. We do not sell to patients.

Licochalcone C
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1350Check With Us
200mg$2025Check With Us
500mg$3415Check With Us

Cat #: V22553 CAS #: 144506-14-9 Purity ≥ 98%

Description: Licochalcone C is a naturally occuring chalcone compound and a potent inhibitor of lipopolysaccharide-interferon-γ inflammation.

References: Zhenghong Guo, et al. Chemical profile and inhibition of α-glycosidase and protein tyrosine phosphatase 1B (PTP1B) activities by flavonoids from licorice (Glycyrrhiza uralensis Fisch). journal of functional foods 14 ( 2015 ) 324-336.

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Molecular Weight (MW)338.40
Molecular FormulaC21H22O4
CAS No.144506-14-9
SMILES CodeO=C(C1=CC=C(O)C=C1)/C=C/C2=CC=C(O)C(C/C=C(C)\C)=C2OC
SynonymsLicochalcone C; Licochalcone-C; LicoC; Lico-C; Lico C;
ProtocolIn VitroLicochalcone C could inhibit α- glucosidase, with IC50s of <100 nM and 92.43 μM for α- glucosidase and PTP1B, respectively.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9551 mL14.7754 mL29.5508 mL59.1017 mL
5mM0.5910 mL2.9551 mL5.9102 mL11.8203 mL
10mM0.2955 mL1.4775 mL2.9551 mL5.9102 mL
20mM0.1478 mL0.7388 mL1.4775 mL2.9551 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.