Levothyroxine (L-Thyroxine; T4)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $600 | Check With Us |
| 25g | $1100 | Check With Us |
| 50g | $1650 | Check With Us |
: Cat #: V5314 CAS #: 51-48-9 (freebase) Purity ≥ 98%
Description: Levothyroxine (also known as L-Thyroxine; T4), a synthetic hormone derived from the thyroid gland, is used in the treatment of hypothyroidism (deficiency of the thyroid hormones).
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- Physicochemical and Storage Information
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| Molecular Weight (MW) | 776.87 |
|---|---|
| Molecular Formula | C15H11I4NO4 |
| CAS No. | 51-48-9 (freebase) |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | OC([C@@H](N)CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(O)C(I)=C2)=O |
| Synonyms | L-Thyroxin, L Thyroxin, T4, Levothyroxine sodium, Levothyroxine sodium pentahydrate, Thyroxine |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.2872 mL | 6.4361 mL | 12.8722 mL | 25.7443 mL |
| 5mM | 0.2574 mL | 1.2872 mL | 2.5744 mL | 5.1489 mL |
| 10mM | 0.1287 mL | 0.6436 mL | 1.2872 mL | 2.5744 mL |
| 20mM | 0.0644 mL | 0.3218 mL | 0.6436 mL | 1.2872 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.