Levoketoconazole [(-)-Ketoconazol; (-)-R 41400]
This product is for research use only, not for human use. We do not sell to patients.
![Levoketoconazole [(-)-Ketoconazol; (-)-R 41400]](https://invivochem.net/wp-content/uploads/2023/05/637440723225394989910708168.gif "Levoketoconazole [(-)-Ketoconazol; (-)-R 41400]")
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $990 | Check With Us |
| 500mg | $1650 | Check With Us |
| 1g | $2475 | Check With Us |
: Cat #: V24011 CAS #: 142128-57-2 Purity ≥ 99%
Description: Levoketoconazole [(-)-Ketoconazole ((-)-R 41400)], the levo-enantiomer of Ketoconazole, is useful for treatment of Cushing's Syndrome.
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| Molecular Weight (MW) | 531.43 |
|---|---|
| Molecular Formula | C26H28Cl2N4O4 |
| CAS No. | 142128-57-2 |
| SMILES Code | CC(N1CCN(C2=CC=C(OC[C@H]3O[C@@](C4=CC=C(Cl)C=C4Cl)(CN5C=CN=C5)OC3)C=C2)CC1)=O |
| Synonyms | 2S,4R-Ketoconazole; Levoketoconazole; Normocort; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.8817 mL | 9.4086 mL | 18.8172 mL | 37.6343 mL |
| 5mM | 0.3763 mL | 1.8817 mL | 3.7634 mL | 7.5269 mL |
| 10mM | 0.1882 mL | 0.9409 mL | 1.8817 mL | 3.7634 mL |
| 20mM | 0.0941 mL | 0.4704 mL | 0.9409 mL | 1.8817 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.