Levodropropizine (DF-526)

This product is for research use only, not for human use. We do not sell to patients.

Levodropropizine (DF-526)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$400Check With Us
2g$650Check With Us
5g$1000Check With Us

Cat #: V1225 CAS #: 99291-25-5 Purity ≥ 98%

Description: Levodropropizine [(S)-(-)-Dropropizine; DF 526; DF-526; DF526; Levotuss], the S-isomer of dropropizine, is a histamine receptor inhibitor used as a cough suppressant.

References: Zanasi A, et al. Levodropropizine for treating cough in adult and children: a meta-analysis of published studies. Multidiscip Respir Med. 2015 May 31;10(1):19.

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Molecular Weight (MW)236.31
Molecular FormulaC13H20N2O2
CAS No.99291-25-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 47 mg/mL (198.9 mM)r
Water: 15 mg/mL (63.5 mM)r
Ethanol: 47 mg/mL (198.9 mM)
Synonyms(S)-(-)-Dropropizine; DF-526; Levodropropizine; DF 526; DF526; Levotuss
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.2317 mL21.1586 mL42.3173 mL84.6346 mL
5mM0.8463 mL4.2317 mL8.4635 mL16.9269 mL
10mM0.4232 mL2.1159 mL4.2317 mL8.4635 mL
20mM0.2116 mL1.0579 mL2.1159 mL4.2317 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.