Leucovorin Calcium
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 25g | $550 | Check With Us |
| 50g | $900 | Check With Us |
| 100g | $1350 | Check With Us |
: Cat #: V2027 CAS #: 1492-18-8 Purity ≥ 98%
Description: Leucovorin calcium, a reduced folic acid and an active metabolite of folic acid, is a derivative of folic acid which can be used to increase levels of folic acid under conditions favoring folic acid inhibition.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 601.58 |
|---|---|
| Molecular Formula | C21H25CaN7O7.5H2O |
| CAS No. | 1492-18-8 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: <1 mg/mLr |
| Water: 40 mg/mL (66.5 mM)r | |
| Ethanol: <1 mg/mL | |
| SMILES Code | O=C([O-])CC[C@@H](C([O-])=O)NC(C1=CC=C(NCC2N(C=O)C3=C(NC(N)=NC3=O)NC2)C=C1)=O.[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[Ca+2] |
| Synonyms | Folinic acid; Folinic acid calcium salt pentahydrate; Leucovorin calcium hydrate; Leucovorin Calcium; Calcium Folinate |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.6623 mL | 8.3114 mL | 16.6229 mL | 33.2458 mL |
| 5mM | 0.3325 mL | 1.6623 mL | 3.3246 mL | 6.6492 mL |
| 10mM | 0.1662 mL | 0.8311 mL | 1.6623 mL | 3.3246 mL |
| 20mM | 0.0831 mL | 0.4156 mL | 0.8311 mL | 1.6623 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.