Lercanidipine HCl (REC 15-237, Lercadip, Lerdip, Zanidip)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
1g	$550	Check With Us
5g	$145	Check With Us
10g	$2222	Check With Us

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Cat #: V23311 CAS #: 132866-11-6 Purity ≥ 99%

Description: Lercanidipine HCl (REC-15-237, Lercadip, Lerdip, Zanidip) is a 3rd generation and lipophilic CCB (calcium channel blocker) of the dihydropyridine class and a medication used to treat high blood pressure, with long lasting antihypertensive action and reno-protective effect.

References: Barrios, V., et al., Lercanidipine is an effective and well tolerated antihypertensive drug regardless the cardiovascular risk profile: The LAURA study. Int J Clin Pract, 2006. 60(11): p. 1364-70.

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Molecular Weight (MW)	648.19
Molecular Formula	C36H42ClN3O6
CAS No.	132866-11-6
Synonyms	Corifeo; Lerkamen; Renovia; Vasodip; R 75; R-75; R75

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.5428 mL	7.7138 mL	15.4276 mL	30.8552 mL
5mM	0.3086 mL	1.5428 mL	3.0855 mL	6.1710 mL
10mM	0.1543 mL	0.7714 mL	1.5428 mL	3.0855 mL
20mM	0.0771 mL	0.3857 mL	0.7714 mL	1.5428 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.