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| Size | Price | Stock |
|---|---|---|
| 5mg | $250 | 3-6 Days |
| 10mg | $450 | 3-6 Days |
| 25mg | $750 | 3-6 Days |
| 50mg | $1250 | 3-6 Days |
: Cat #: V41895 CAS #: 2304621-06-3 Purity ≥ 99%
Description: IMT1B (LDC-203974; IMT-1B) is a novel first-in-class and allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) with the potential for the treatment of cancer. POLRMT is a human mitochondrial RNA polymerase (POLRMT) and is essential for mtDNA transcription as well as biogenesis of the oxidative phosphorylation (OXPHOS) system.
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- Quality Control Documentation
| Molecular Weight (MW) | 473.88 |
|---|---|
| Molecular Formula | C24H21ClFNO6 |
| CAS No. | 2304621-06-3 |
| SMILES Code | O=C([C@@H]1CN(C([C@H](OC2=CC(O3)=C(C=C2)C(C4=CC=C(F)C=C4Cl)=CC3=O)C)=O)CCC1)O |
| Synonyms | LDC 203974; IMT1B; LDC203974; IMT-1B |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.1102 mL | 10.5512 mL | 21.1024 mL | 42.2048 mL |
| 5mM | 0.4220 mL | 2.1102 mL | 4.2205 mL | 8.4410 mL |
| 10mM | 0.2110 mL | 1.0551 mL | 2.1102 mL | 4.2205 mL |
| 20mM | 0.1055 mL | 0.5276 mL | 1.0551 mL | 2.1102 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.