Latanoprost lactone diol

This product is for research use only, not for human use. We do not sell to patients.

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Cat #: V40392 CAS #: 145667-75-0 Purity ≥ 99%

Description: Latanoprost lactone diol is an intermediate used in the synthesis of Latanoprost, which is a FP receptor agonist (EC50 = 3.6 nM for human FP receptors) with the potential for the treatment of glaucoma.

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Molecular Weight (MW)	304.38
Molecular Formula	C₁₈H₂₄O₄
CAS No.	145667-75-0
Synonyms	Latanoprost lactone diol

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.2854 mL	16.4268 mL	32.8537 mL	65.7073 mL
5mM	0.6571 mL	3.2854 mL	6.5707 mL	13.1415 mL
10mM	0.3285 mL	1.6427 mL	3.2854 mL	6.5707 mL
20mM	0.1643 mL	0.8213 mL	1.6427 mL	3.2854 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.