LANREOTIDE
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1350 | Check With Us |
| 250mg | $2380 | Check With Us |
| 500mg | $3570 | Check With Us |
: Cat #: V4355 CAS #: 108736-35-2 Purity ≥ 98%
Description: Lanreotide (Ipstyl; Somatulin; BIM-23014; Lanreotide Autogel), a synthetic somatostatin analogue, is a medication used in the management of acromegaly and symptoms caused by neuroendocrine tumors, most notably carcinoid syndrome.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 1096.32 |
|---|---|
| Molecular Formula | C54H69N11O10S2 |
| CAS No. | 108736-35-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | CC([C@@H]1NC([C@@H](NC([C@H](NC([C@@H](NC([C@@H](NC([C@@H](Cc(cc2)cc3c2cccc3)N)=O)CSSC[C@@H](C(N[C@H](C(N)=O)[C@H](O)C)=O)NC1=O)=O)Cc4ccc(O)cc4)=O)Cc(c[nH]5)c6c5cccc6)=O)CCCCN)=O)C |
| Synonyms | Somatuline; Lanreotide; Ipstyl; BIM 23014; Somatulin; Lanreotide Autogel. |
| Protocol | In Vitro | Lanreotide results in a dose-dependent decrease in GH3 cell colony forming units. Lanreotide at concentrations of 1, 10, 100, and 1000 nM results in cell survival rates of 75, 56, 39 and 27% respectively. The IC50 is 57 nM. Lanreotide (BIM 23014) (100 nM; 0-48 h) enhanced radiation-induced apoptosis. |
|---|---|---|
| In Vivo | Lanreotide (2.5-10mg/kg; s.c.; daily for 5 days) results in tumor growth inhibition. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 0.9121 mL | 4.5607 mL | 9.1214 mL | 18.2428 mL |
| 5mM | 0.1824 mL | 0.9121 mL | 1.8243 mL | 3.6486 mL |
| 10mM | 0.0912 mL | 0.4561 mL | 0.9121 mL | 1.8243 mL |
| 20mM | 0.0456 mL | 0.2280 mL | 0.4561 mL | 0.9121 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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V1
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.