L-Hyoscyamine (Daturine)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
5g | $320 | Check With Us |
10g | $550 | Check With Us |
20g | $825 | Check With Us |
Cat #: V1200 CAS #: 101-31-5 Purity ≥ 98%
Description: L-Hyoscyamine (Daturine), a natural tropane alkaloid and plant toxin, is the the levo-isomer of atropine and is used for controlling symptoms associated with disorders of the gastrointestinal (GI) tract.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
Molecular Weight (MW) | 289.37 |
---|---|
Molecular Formula | C17H23NO3 |
CAS No. | 101-31-5 |
Storage | -20℃ for 3 years in powder formrr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 58 mg/mL (200.4 mM)rr |
Water: <1 mg/mLrr | |
Ethanol: 58 mg/mL (200.4 mM) | |
Solubility In Vivo | 30% Propylene glycol, 5% Tween 80, 65% D5W: 5 mg/mL |
Synonyms | Daturine |
Protocol | In Vivo | L-Hyoscyamine (Daturine; 5-20 mg/kg; iv) prolongs the migrating MMC cycle length |
---|---|---|
Animal model | Rats | |
Dosages | 5, 10, 20 mg/kg |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 3.4558 mL | 17.2789 mL | 34.5578 mL | 69.1157 mL |
5mM | 0.6912 mL | 3.4558 mL | 6.9116 mL | 13.8231 mL |
10mM | 0.3456 mL | 1.7279 mL | 3.4558 mL | 6.9116 mL |
20mM | 0.1728 mL | 0.8639 mL | 1.7279 mL | 3.4558 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.