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Kynurenic acid sodium

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Kynurenic acid sodium
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Size Price Stock
10g$600To Be Confirmed
25g$1100To Be Confirmed
50g$1650To Be Confirmed

Cat #: V31254 CAS #: 2439-02-3 Purity ≥ 99%

Description: Kynurenic acid sodium is an endogenous tryptophan metabolite with activity against NMDA, glutamate, α7 nicotinic acetylcholine receptors.

References: Małaczewska J, et al. Effect of oral administration of kynurenic acid on the activity of the peripheral blood leukocytes in mice. Cent Eur J Immunol. 2014;39(1):6-13.

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Molecular Weight (MW)212.16
Molecular FormulaC₁₀H₇NNaO₃
CAS No.2439-02-3
ProtocolIn VivoKynurenic acid affects the activity of leukocytes in the peripheral blood of mice, although the lowest one (2.5 mg/L) has the most profound influence in contrast to the highest one (250 mg/L), which produces the weakest effect. The lowest Kynurenic acid dose stimulates the proliferative response of T lymphocytes (p<0.05), after 7 and 28 days of administering the acid to the animals
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.7134 mL23.5671 mL47.1342 mL94.2685 mL
5mM0.9427 mL4.7134 mL9.4268 mL18.8537 mL
10mM0.4713 mL2.3567 mL4.7134 mL9.4268 mL
20mM0.2357 mL1.1784 mL2.3567 mL4.7134 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

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C1
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Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.