KN-92 Hydrochloride

This product is for research use only, not for human use. We do not sell to patients.

KN-92 Hydrochloride
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1250Check With Us
500mg$1850Check With Us
1g$2275Check With Us

Cat #: V2803 CAS #: 1431698-47-3 Purity ≥ 98%

Description: KN-92 Hydrochloride, the hydrochloride salt of KN-92, is an inactive derivative of KN-93.

References: An P, et al. KN-93, a specific inhibitor of CaMKII inhibits human hepatic stellate cell proliferation in vitro. World J Gastroenterol. 2007;13(9):1445-1448.

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Product Promise

Promise
Molecular Weight (MW)493.45
Molecular FormulaC24H26Cl2N2O3S
CAS No.1431698-47-3
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: ~25mg/mLrr
Water: N/Arr
Ethanol: N/A
SynonymsKN-92 HCl; KN-92; KN 92; KN92
ProtocolIn VitroKN-93 (5-50μM; 24 hours) inhibits LX-2 cell growth and KN-92 (5-50μM; 24 hours) is ineffective in blocking cell growth
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0265 mL10.1327 mL20.2655 mL40.5310 mL
5mM0.4053 mL2.0265 mL4.0531 mL8.1062 mL
10mM0.2027 mL1.0133 mL2.0265 mL4.0531 mL
20mM0.1013 mL0.5066 mL1.0133 mL2.0265 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.