KH7
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50mg | $1350 | To Be Confirmed |
| 100mg | $2025 | To Be Confirmed |
| 200mg | $3035 | To Be Confirmed |
: Cat #: V23223 CAS #: 330676-02-3 Purity ≥ 99%
Description: KH7 (KH-7) is a novel and potent Inhibitor of Sac (soluble adenylyl cyclase) with IC50s of 3-10 μM against both recombinant purified human sACt protein and heterologously expressed sACt in cellular assays.
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- Protocol
- Related Biological Data
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- Quality Control Documentation
| Molecular Weight (MW) | 419.30 |
|---|---|
| Molecular Formula | C17H15BrN4O2S |
| CAS No. | 330676-02-3 |
| Protocol | In Vitro | KH7 (10 μM) blocks this capacitation-induced cAMP increase. At higher concentrations (50 μM), 5- to 10-fold above its IC50 but still selective for sAC relative to tmACs, KH7 resulted in a significant decrease in the basal cAMP accumulation in sperm regardless of the incubation medium |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3849 mL | 11.9246 mL | 23.8493 mL | 47.6985 mL |
| 5mM | 0.4770 mL | 2.3849 mL | 4.7699 mL | 9.5397 mL |
| 10mM | 0.2385 mL | 1.1925 mL | 2.3849 mL | 4.7699 mL |
| 20mM | 0.1192 mL | 0.5962 mL | 1.1925 mL | 2.3849 mL |
The molarity calculator equation
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.