This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 1mg | $140 | To Be Confirmed |
| 5mg | $340 | To Be Confirmed |
| 10mg | $580 | To Be Confirmed |
: Cat #: V23093 CAS #: 233277-99-1 Purity ≥ 99%
Description: K-11777 (APC-3316; K-777) is a novel, orally bioactive and irreversible cysteine protease inhibitor as well as a selective CCR4 antagonist with anticancer and antiviral activity. K777 irreversibly inhibits Cruzain which is the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. Thus, K777 has a broad-spectrum antiviral activity by targeting cathepsin-mediated cell entry. K777 also inhibits SARS-CoV and EBOV pseudovirus entry with IC50 values of 0.68 nM and 0.87 nM, respectively.
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| Molecular Weight (MW) | 574.73352 |
|---|---|
| Molecular Formula | C32H38N4O4S |
| CAS No. | 233277-99-1 |
| Storage | Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Synonyms | APC 3316 K-11777 K-777APC3316 K11777 K777APC-3316 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.7399 mL | 8.6997 mL | 17.3994 mL | 34.7987 mL |
| 5mM | 0.3480 mL | 1.7399 mL | 3.4799 mL | 6.9597 mL |
| 10mM | 0.1740 mL | 0.8700 mL | 1.7399 mL | 3.4799 mL |
| 20mM | 0.0870 mL | 0.4350 mL | 0.8700 mL | 1.7399 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.