JNJ-42165279

This product is for research use only, not for human use. We do not sell to patients.

JNJ-42165279
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$780Check With Us
250mg$1280Check With Us
500mg$1920Check With Us

Cat #: V4504 CAS #: 1346528-50-4 Purity ≥ 98%

Description: JNJ-42165279 is a novel, potent, covalent and selective FAAH (fatty acid amide hydrolase) inhibitor with IC50 of 70 ± 8 nM and 313 ± 28 nM for hFAAH and rFAAH, respectively.

References: Keith JM, et al. Preclinical Characterization of the FAAH Inhibitor JNJ-42165279. ACS Med Chem Lett. 2015 Nov 2;6(12):1204-8.

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Product Promise

Promise
Molecular Weight (MW)410.80
Molecular FormulaC18H17ClF2N4O3
CAS No.1346528-50-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C(N1CCN(CC2=CC=C(OC(F)(F)O3)C3=C2)CC1)NC4=C(Cl)C=CN=C4
SynonymsJNJ-42165279; JNJ 42165279; JNJ42165279
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4343 mL12.1714 mL24.3427 mL48.6855 mL
5mM0.4869 mL2.4343 mL4.8685 mL9.7371 mL
10mM0.2434 mL1.2171 mL2.4343 mL4.8685 mL
20mM0.1217 mL0.6086 mL1.2171 mL2.4343 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.