JNJ-42041935
This product is for research use only, not for human use. We do not sell to patients.
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Size | Price | Stock |
---|---|---|
250mg | $980 | Check With Us |
500mg | $1420 | Check With Us |
1g | $2130 | Check With Us |
Cat #: V3444 CAS #: 1193383-09-3 Purity ≥ 98%
Description: JNJ-42041935 is a novel, potent, competitive, reversible, and selective inhibitor of prolyl hydroxylase PHD with pKi values of 7.91±0.04, 7.29 ±0.05, and 7.65±0.09 for PHD1, PHD2, and PHD3, respectively.
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Molecular Weight (MW) | 346.65 |
---|---|
Molecular Formula | C12H6ClF3N4O3 |
CAS No. | 1193383-09-3 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
SMILES Code | ClC1=CC2=C(NC(N3C=C(C(O)=O)C=N3)=N2)C=C1OC(F)(F)F |
Synonyms | JNJ-42041935; JNJ 42041935; JNJ42041935 |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.8848 mL | 14.4238 mL | 28.8475 mL | 57.6951 mL |
5mM | 0.5770 mL | 2.8848 mL | 5.7695 mL | 11.5390 mL |
10mM | 0.2885 mL | 1.4424 mL | 2.8848 mL | 5.7695 mL |
20mM | 0.1442 mL | 0.7212 mL | 1.4424 mL | 2.8848 mL |
The molarity calculator equation
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.