Isavuconazole (BAL-4815; RO-0094815)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
250mg | $850 | To Be Confirmed |
500mg | $1350 | To Be Confirmed |
1g | $2025 | To Be Confirmed |
Cat #: V5312 CAS #: 241479-67-4 Purity ≥ 98%
Description: Isavuconazole (formerly also known as BAL-4815; RO-0094815; Cresemba), a water-soluble triazole antifungal agent, is a novel and potent inhibitor of CYP3A4 with broad-spectrum antifungal activity.
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Molecular Weight (MW) | 437.47 |
---|---|
Molecular Formula | C22H17F2N5OS |
CAS No. | 241479-67-4 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
SMILES Code | N#CC1=CC=C(C2=CSC([C@@H]([C@@](O)(C3=CC(F)=CC=C3F)CN4N=CN=C4)C)=N2)C=C1 |
Synonyms | BAL-4815; BAL 4815; BAL4815; ; RO 0094815; RO-0094815; BAL-8557-002; RO0094815; BAL 8557-002; BAL8557-002; Isavuconazole; trade name Cresemba |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.2859 mL | 11.4294 mL | 22.8587 mL | 45.7174 mL |
5mM | 0.4572 mL | 2.2859 mL | 4.5717 mL | 9.1435 mL |
10mM | 0.2286 mL | 1.1429 mL | 2.2859 mL | 4.5717 mL |
20mM | 0.1143 mL | 0.5715 mL | 1.1429 mL | 2.2859 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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Volume(start)
V1
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Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.