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Isavuconazole (BAL-4815; RO-0094815)

This product is for research use only, not for human use. We do not sell to patients.

Isavuconazole (BAL-4815; RO-0094815)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$850To Be Confirmed
500mg$1350To Be Confirmed
1g$2025To Be Confirmed

Cat #: V5312 CAS #: 241479-67-4 Purity ≥ 98%

Description: Isavuconazole (formerly also known as BAL-4815; RO-0094815; Cresemba), a water-soluble triazole antifungal agent, is a novel and potent inhibitor of CYP3A4 with broad-spectrum antifungal activity.

References: Seifert H, et al. In vitro activities of isavuconazole and other antifungal agents against Candida bloodstream isolates. Antimicrob Agents Chemother. 2007 May;51(5):1818-21.

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Product Promise

Promise
Molecular Weight (MW)437.47
Molecular FormulaC22H17F2N5OS
CAS No.241479-67-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeN#CC1=CC=C(C2=CSC([C@@H]([C@@](O)(C3=CC(F)=CC=C3F)CN4N=CN=C4)C)=N2)C=C1
SynonymsBAL-4815; BAL 4815; BAL4815; ; RO 0094815; RO-0094815; BAL-8557-002; RO0094815; BAL 8557-002; BAL8557-002; Isavuconazole; trade name Cresemba
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.2859 mL11.4294 mL22.8587 mL45.7174 mL
5mM0.4572 mL2.2859 mL4.5717 mL9.1435 mL
10mM0.2286 mL1.1429 mL2.2859 mL4.5717 mL
20mM0.1143 mL0.5715 mL1.1429 mL2.2859 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.