Imatinib D4

This product is for research use only, not for human use. We do not sell to patients.

Imatinib D4
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1mg$2703-6 Days
email: sales@invivochem.com        sales@invivochem.cn

Cat #: V40298 CAS #: 1134803-16-9 Purity ≥ 99%

Description: Imatinib D4 is the tetra-deuterated form of Imatinib (STI571), Imatinib (Gleevec or Glivec) is an orally bioavailable multi-kinase inhibitor of v-Abl, c-Kit and PDGFR approved for cancer treatment (e.g. a number of leukemias).

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Molecular Weight (MW)497.63
Molecular FormulaC29H27D4N7O
CAS No.1134803-16-9
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0095 mL10.0476 mL20.0953 mL40.1905 mL
5mM0.4019 mL2.0095 mL4.0191 mL8.0381 mL
10mM0.2010 mL1.0048 mL2.0095 mL4.0191 mL
20mM0.1005 mL0.5024 mL1.0048 mL2.0095 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Concentration
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.