IEM 1754 2HBr
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $1150 | Check With Us |
| 1g | $1725 | Check With Us |
| 5g | $5175 | Check With Us |
: Cat #: V1088 CAS #: 162831-31-4 Purity ≥ 98%
Description: IEM 1754 2HBr (IEM-1754; IEM 1754; IEM1754), the dihydrobromide salt of IEM-1754, is a selective voltage-dependent open-channel blocker of AMPA/kainate receptors with important biological activity.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 412.25 |
|---|---|
| Molecular Formula | C16H30N2.2HBr |
| CAS No. | 162831-31-4 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 82 mg/mL (198.9 mM)rr |
| Water: 82 mg/mL (198.9 mM)rr | |
| Ethanol: <1 mg/mL | |
| Solubility In Vivo | 30% propylene glycol, 5% Tween 80, 65% D5W: 30 mg/mL |
| SMILES Code | NCCCCCNCC1(C2)CC3CC2CC(C3)C1.[H]Br.[H]Br |
| Synonyms | IEM-1754; IEM-1754 dihydrobromide; IEM 1754; IEM1754; IEM1754 dihydrobromide; IEM-1754 2HBr; IEM 1754 dihydrobromide; IEM 1754 2HBr; IEM1754 2HBr |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.4257 mL | 12.1286 mL | 24.2571 mL | 48.5143 mL |
| 5mM | 0.4851 mL | 2.4257 mL | 4.8514 mL | 9.7029 mL |
| 10mM | 0.2426 mL | 1.2129 mL | 2.4257 mL | 4.8514 mL |
| 20mM | 0.1213 mL | 0.6064 mL | 1.2129 mL | 2.4257 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.