ID-8

This product is for research use only, not for human use. We do not sell to patients.

ID-8
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$600Check With Us
500mg$1050Check With Us
1g$1575Check With Us

Cat #: V1953 CAS #: 147591-46-6 Purity ≥ 98%

Description: ID-8 is a novel and potent small molecule DYRK (Dual-specificity tyrosine phosphorylation-regulated kinase) inhibitor that sustains embryonic stem cell self-renewal in long-term culture.

References: Hasegawa, K., et al., Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion. Stem Cells Transl Med, 2012. 1(1): p. 18-28.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)298.29
Molecular FormulaC16H14N2O4
CAS No.147591-46-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 60 mg/mL (201.1 mM)r
Water: <1 mg/mLr
Ethanol: 2 mg/mL (6.7 mM)
SynonymsID-8; ID 8; ID8
ProtocolIn VitroID-8 (0.1-10 μM) increases human embryonic stem cell (hESC) survival.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.3524 mL16.7622 mL33.5244 mL67.0488 mL
5mM0.6705 mL3.3524 mL6.7049 mL13.4098 mL
10mM0.3352 mL1.6762 mL3.3524 mL6.7049 mL
20mM0.1676 mL0.8381 mL1.6762 mL3.3524 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.