Ibotenic Acid [(RS)-Ibotenic acid; DL-Ibotenic acid]
This product is for research use only, not for human use. We do not sell to patients.
![Ibotenic Acid [(RS)-Ibotenic acid; DL-Ibotenic acid]](https://invivochem.net/wp-content/uploads/2023/05/6374167693676059941396864166.png "Ibotenic Acid [(RS)-Ibotenic acid; DL-Ibotenic acid]")
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50mg | $1050 | Check With Us |
| 100mg | $1650 | Check With Us |
| 200mg | $2475 | Check With Us |
: Cat #: V22375 CAS #: 2552-55-8 Purity ≥ 98%
Description: Ibotenic Acid [(RS)-Ibotenic acid; DL-Ibotenic acid] is a highly potent excitatory amino acid agonist with activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites.
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| Molecular Weight (MW) | 158.11 |
|---|---|
| Molecular Formula | C5H6N2O4 |
| CAS No. | 2552-55-8 |
| SMILES Code | O=C(O)C(N)C(ON1)=CC1=O |
| Protocol | In Vitro | Ibotenic acid (Ibo) acts on NMDA and trans-ACPD receptors in the CNS, although only activation of NMDA receptors is associated with Ibo neurotoxicity. Ibotenic acid is toxic to cortical neurons, exposure for 5 minutes, EC50=77.3±8 μM (n=5), measured by releasing lactate dehydrogenase into the medium. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 6.3247 mL | 31.6236 mL | 63.2471 mL | 126.4942 mL |
| 5mM | 1.2649 mL | 6.3247 mL | 12.6494 mL | 25.2988 mL |
| 10mM | 0.6325 mL | 3.1624 mL | 6.3247 mL | 12.6494 mL |
| 20mM | 0.3162 mL | 1.5812 mL | 3.1624 mL | 6.3247 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.